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Post-Pandemic TB Surge in Asia-Pacific

In Indonesia, TB is the fourth-highest cause of death overall, and among those aged 15 to 49 years, it is the number one cause of death by a contagious disease…reports Asian Lite News

Many developing countries in the Asia-Pacific region, including the Philippines, still have a high tuberculosis (TB) incidence rate, according to an article published in the Asian Development Blog of the Asian Development Bank (ADB).

Citing World Health Organization (WHO) data, the recently published article said the highly infectious disease “remains rife” in the region, with Southeast Asia responsible for 46 per cent of global infections in 2022, “the highest in any region”, Xinhua news agency reported.

The article also said the pandemic devastated national TB prevention and treatment programmes, causing an estimated half a million excess deaths between 2020 and 2022.

However, the good news is that there has been a post-pandemic recovery in the number of people diagnosed with and treated for TB, helping to reduce the damage done by the pandemic, it added.

According to the WHO Global Tuberculosis Report 2023, the Philippines, along with Indonesia, Mongolia, Papua New Guinea, and Vietnam, have some of the highest levels of TB in the region — around 700,000 people out of a population of 115 million have active TB.

Nearly 10 million people in the Philippines reside in impoverished urban areas. Poverty and overcrowding, along with poorly-resourced public health services, are major factors in the widespread incidence of TB in the country, according to The Lancet.

In Indonesia, TB is the fourth-highest cause of death overall, and among those aged 15 to 49 years, it is the number one cause of death by a contagious disease.

TB, an airborne disease spawned by urban poverty, is currently the world’s second-biggest infectious killer after Covid-19. Many countries are working to eliminate TB by 2030, which aligns with the WHO’s End Tuberculosis Strategy.

The article said adapting practices such as mask-wearing and improved hygiene at home and work that proved effective against Covid-19 could play an important role in helping Asia and the Pacific rid themselves of TB permanently.

However, socioeconomic factors, including poverty, overcrowding, poor sanitation, lack of infrastructure, and inadequate public health systems, allow the disease to remain endemic, it added.

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BRICS to study intersection of Covid, TB

The four countries currently rank second to fifth in the number of cases of Covid-19 and belong to 24 countries recognised by the WHO with the highest burden of tuberculosis in the world….reports Asian Lite News

A consortium of doctors and researchers from India, Brazil, Russia, and South Africa have partnered to conduct a study on the epidemiological impact and intersection of the Covid-19 and Tuberculosis (TB) pandemics in these countries.

In a statement, India’s Science and Technology Ministry said that under this joint research, the teams from these countries will explore the negative impact of the Covid-19 pandemic on the epidemiological characteristics of TB infection and search for mechanisms responsible for the interaction of these two processes.

“They will also search for strategies to mitigate the negative consequences of the pandemic and develop individual recommendations for each participating country, which can help overcome the impact of epidemics of respiratory viral diseases on the epidemic of tuberculosis,” it said.

The four countries currently rank second to fifth in the number of cases of Covid-19 and belong to 24 countries recognised by the WHO with the highest burden of tuberculosis in the world.

Moreover, BRICS countries have the largest number of cases of drug-resistant tuberculosis.

“Hence the research will be conducted in these 4 BRICS countries where one of the highest-burden rates of both Covid-19 and tuberculosis has been recorded simultaneously,” the statement said.

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This research supported by the Department of Science and Technology is being led by Prof Urvashi B. Singh from All India Institute of Medical Sciences, New Delhi.

The teams will assess the impact of Covid-19 on trends in the structure of the tuberculosis population, primarily through the interaction between scientists from Russia and India.

The teams from Brazil and South Africa will evaluate the impact of tuberculosis on the clinical course and treatment outcomes for Covid-19 at the individual level.

The impact of the Covid-19 pandemic and associated restrictive measures on morbidity and tuberculosis-related mortality will be assessed using mathematical modelling.

This collaborative research will provide a differentiated country-based assessment of the negative consequences of Covid-19 on the provision of anti-tuberculosis care, its continuity, consistency, and adequacy through a comparative analysis of the inter-country similarities and differences in the interaction of the two epidemics at the population and individual level.

“The analysis will provide insights into the most important points of application for epidemiological, medico-social, clinical, and socio-economic interventions that are expected to reduce morbidity and mortality from the interaction of Covid-19 and TB in both the short and long term,” the ministry said.

It said that the approach used will allow the development of a unique platform for mathematical modelling of the epidemic tuberculosis process, which will also support and enhance epidemic modelling capabilities in BRICS countries and thus provide a solid foundation for future collaborative modelling research.

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