Mutant – Central News Hub

Presence of double mutant variant confirmed in Chandigarh

The presence of the double mutant B.1.617 variant having the signature mutations L452R and E484Q has been confirmed in 22 per cent (5/23) of the samples after sequencing…reports Asian Lite News

Reports of sequencing of SARS-CoV-2 from 23 nasopharyngeal swab samples of Covid-19 patients sent from PGIMER in Chandigarh were received on Thursday from NCDC in New Delhi, the hospital said on Sunday.

The presence of the double mutant B.1.617 variant having the signature mutations L452R and E484Q has been confirmed in 22 per cent (5/23) of the samples after sequencing, said Jagat Ram, Director PGIMER.

He further stated that the B.1.617 variant first identified in India last year has been found in more than 40 countries and has recently been classified as a “variant of concern” (VOC) by World Health Organisation (WHO).

It has been found by researchers that the mutations in the double-mutant strain render it to be more transmissible and vaccine -induced antibodies are somewhat less potent in neutralizing this variant.

“The surge of cases during the second wave of Covid-19 pandemic has somewhat been attributed to the B.1.617 variant strain”, added Ram.

Giving further details on the findings, the Director said in a statement, “Of the other samples, the UK variant B.1.1.7 which is also a VOC and associated with higher transmissibility was found in 39 per cent (9/23) samples.

“The UK variant B.1.1.7 carries the signature mutations N501Y, P681H, 69/70 D f the SARS-CoV-2 virus.”

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Meanwhile, Covid numbers brought a heave of relief as the daily figures dropped below the 3-lakh mark for the first time in nearly a month.

In the last 24 hours, 2,81,386 new corona cases were reported — lowest in 25 days, and 4,106 fatalities, the Union Ministry of Health and Family Welfare said.

Kerala covid toll rises

On May 12, India recorded 4,205 fresh Covid deaths, the highest ever, while on May 7, the country had recorded its highest ever cases of 4,14,188.

India’s total tally of Covid-19 cases now stands at 2,49,65,463 with 35,16,997 active cases and 2,74,390 deaths so far.

According to the Health Ministry, a total of 3,78,741 people have been discharged in the last 24 hours, with 2,11,74,076 being cured from Covid till date.

The Health Ministry said that a total of 18,29,26,460 people have been vaccinated so far in the country, including 6,91,211 who were administered vaccines in the last 24 hours.

According to the Indian Council of Medical Research (ICMR), 31,64,23,658

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DR FAUCI: ‘Covaxin can neutralise 617 Variant of Covid-19′

A breakthrough in the fight against Covid-19. White House chief medical adviser and America’s top pandemic expert Dr Anthony Fauci said Covaxin, India’s home-grown COVID-19 vaccine, has been found to neutralise the 617 variant of the deadly virus.

“This is something where we’re still gaining data on a daily basis. But the most recent data, was looking at convalescent Sera of COVID-19 cases and people who received the vaccine used in India, the Covaxin. It was found to neutralise the 617 variants,” Dr Fauci told reporters at White House.

‘So, despite the real difficulty that we’re seeing in India, vaccination could be a very, very important antidote against this,’ Fauci added.

The New York Times said Covaxin works by teaching the immune system to make antibodies against the SARS-CoV-2 coronavirus. The antibodies attach to viral proteins, such as the so-called spike proteins that stud its surface.

Developed by Bharat Biotech in partnership with National Institute of Virology and the Indian Council of Medical Research, Covaxin was approved for emergency use on January 3. Trial results later showed the vaccine has an efficacy of 78 per cent.